members of both include scientists whose work takes them outside of the established scientific community.
members of both have headquarters and operations on an island.
members of both have to deal with ghosts and phantasmagorical monsters.
both were basically defunct from 1992 forward.
thematically important phrases from lost which appear in ghostbusters:
"i'll fix you, venkman! i'm gonna fix you!"
"we've got work to do."